Longitudinal Predictors of Neurodevelopmental Outcomes in Children with Down Syndrome

Deborah J. Fidler, Kaylyn Van Deusen, Mark A. Prince, Emily K. Schworer, Nancy R. Lee, Jamie O. Edgin, Lina R. Patel, Lisa A. Daunhauer

Research output: Contribution to journalArticlepeer-review


This study examined longitudinal predictors of neurodevelopmental outcomes in children with Down syndrome (DS). Participants were assessed at Wave 1 during infancy on measures of looking behavior and caregivers provided infant sensory ratings. At Wave 2, child-age participants completed a developmental assessment and caregivers provided ratings of executive function, ADHD symptoms, and autism symptoms. Longer looking durations and greater sensory dysregulation during infancy were predictive of higher ADHD symptom ratings and other neurodevelopmental outcomes during childhood. The findings suggest that early indicators of neurodevelopmental dysregulation may be detectable during infancy in DS.

Original languageEnglish (US)
Pages (from-to)280-298
Number of pages19
JournalDevelopmental Neuropsychology
Issue number6
StatePublished - 2023

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology


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