Locally produced autoantibodies in cancer

Sara M. Centuori, Deepta Bhattacharya

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations

Abstract

The function and antigen-specificities of tumor-infiltrating B cells are mostly unknown. In a new study by Mazor et al., matrix metalloproteinase 14 (MMP14), a self-antigen that is overexpressed by ovarian cancers, is shown to drive B cell activation and autoantibody production in tertiary lymphoid structures (Mazor et al., 2022).

Original languageEnglish (US)
Pages (from-to)1110-1111
Number of pages2
JournalCell
Volume185
Issue number7
DOIs
StatePublished - Mar 31 2022

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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