Local fibrinolysis in cerebral venous thrombosis

David A. Griesemer, Andreas A. Theodorou, Robert A. Berg, Thomas D. Spera

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


Extensive cerebral venous sinus thrombosis may cause death or severe neurologic sequelae. A minimally responsive 10-year-old boy with thrombosis of the superior sagittal sinus, left transverse and left sigmoid sinus, torcular, vein of Galen, and straight sinus under-went fibrinolytic therapy with urokinase during transfemoral venous angiography. He improved dramatically during the procedure as antegrade venous flow was re-established. Local thrombolytic therapy may be beneficial for other patients with rapid neurologic deterioration caused by extensive thrombosis of superficial and deep venous structures.

Original languageEnglish (US)
Pages (from-to)78-80
Number of pages3
JournalPediatric Neurology
Issue number1
StatePublished - Feb 1994

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology


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