Lipofuscin granules in normal, benign and malignant human prostatic tissue

Confirmation and extension of the identification and variation of the frequency of lipofuscin granules in sections of specimens of normal, benign and malignant human prostatic tissue by fluorescent microscopy was obtained. However, the suggestion of the possible relationship between the presence of these granules and alterations in the metabolic processes within the prostate occuring in consequence of senescence and/or disease-specific factors is perhaps somewhat questionable as cellular and structural variations ranging from the benign to the most anaplastic were frequently observed in the same microscopic section.