Language mapping in aphasia

Stephen M. Wilson, Dana K. Eriksson, Melodie Yen, Andrew T. Demarco, Sarah M. Schneck, Jillian M. Lucanie

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Recovery from aphasia is thought to depend on neural plasticity, that is, functional reorganization of surviving brain regions such that they take on new or expanded roles in language processing. To make progress in characterizing the nature of this process, we need feasible, reliable, and valid methods for identifying language regions of the brain in individuals with aphasia. This article reviews 3 recent studies from our lab in which we have developed and validated several novel functional magnetic resonance imaging paradigms for language mapping in aphasia. Method: In the 1st study, we investigated the reliability and validity of 4 language mapping paradigms in neurologically normal older adults. In the 2nd study, we developed a novel adaptive semantic matching paradigm and assessed its feasibility, reliability, and validity in individuals with and without aphasia. In the 3rd study, we developed and evaluated 2 additional adaptive paradigms—rhyme judgment and syllable counting—for mapping phonological encoding regions. Results: We found that the adaptive semantic matching paradigm could be performed by most individuals with aphasia and yielded reliable and valid maps of core perisylvian language regions in each individual participant. The psychometric properties of this paradigm were superior to those of other commonly used paradigms such as narrative comprehension and picture naming. The adaptive rhyme judgment paradigm was capable of identifying fronto-parietal phonological encoding regions in individual participants. Conclusion: Adaptive language mapping paradigms offer a promising approach for future research on the neural basis of recovery from aphasia.

Original languageEnglish (US)
Pages (from-to)3937-3946
Number of pages10
JournalJournal of Speech, Language, and Hearing Research
Volume62
Issue number11
DOIs
StatePublished - Nov 2019
Externally publishedYes

ASJC Scopus subject areas

  • Language and Linguistics
  • Linguistics and Language
  • Speech and Hearing

Fingerprint

Dive into the research topics of 'Language mapping in aphasia'. Together they form a unique fingerprint.

Cite this