Laboratory practices for reporting bacterial susceptibility tests that affect antibiotic therapy

Ron B. Schifman, Ales Pindur, John A. Bryan

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Objective. - To evaluate a laboratory-based process for integrating antimicrobial susceptibility, pharmacy, and clinical data with rapid physician notification to improve the care and outcome of patients with bacterial infections. Design. - Randomized case control study comparing standard microbiology reporting method with a targeted notification procedure. Results. - Of 254 cases studied, a discordance between antimicrobial susceptibility test results and antibiotic therapy was detected in 140 (55%) patients and confirmed after clinical review in 49 (19%). Appropriate changes in antibiotic therapy were made significantly sooner and in a significantly higher proportion of cases with targeted notification than with standard reporting procedures. Conclusions. - Utilization of antimicrobial susceptibility results is improved by integrating clinical and therapeutic information to identify cases that require physician notification, as measured by the timeliness and appropriateness of antibiotic treatment.

Original languageEnglish (US)
Pages (from-to)1168-1170
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Issue number11
StatePublished - 1997

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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