Abstract
Adminstration of the serotonin precursor L-tryptophan in a patient with neuroleptic-induced tardive dyskinesia, produced a dramatic reduction in the severity of the abnormal movements within 24 hours. This report supports our hypothesis that alterations in the function of serotoninergic neurotransmission are implicated in the pathophysiology of neuroleptic-induced tardive dyskinesia.
Original language | English (US) |
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Pages (from-to) | 127-130 |
Number of pages | 4 |
Journal | International Journal of Neuroscience |
Volume | 42 |
Issue number | 1-2 |
DOIs | |
State | Published - 1988 |
Keywords
- Dopamine
- Iatrogenic disorder
- L-tryptophan
- Movement disorders
- Serotonin
- Tardive dyskinesia
ASJC Scopus subject areas
- General Neuroscience