Kinetic scheduling of vincristine (NSC-67574) and bleomycin (NSC-125066) in patients with lung cancer and other malignant tumors

R. B. Livingston; G. P. Bodey; J. A. Gottlieb; E. Frei

Kinetic scheduling of vincristine (NSC-67574) and bleomycin (NSC-125066) in patients with lung cancer and other malignant tumors

R. B. Livingston, G. P. Bodey, J. A. Gottlieb, E. Frei

Research output: Contribution to journal › Article › peer-review

Abstract

Forty eight patients received vincristine and bleomycin given in sequential combination. Of 32 evaluable patients, nine had a partial response (28%) including four of 15 with lung cancer (27%) and three of nine with head and neck cancer (33%). The results of sequential combination therapy in lung cancer appear to be superior to those previously reported for bleomycin alone. Toxicity of the combination was no greater than that expected of each agent. There was no significant myelosuppression.

Original language	English (US)
Pages (from-to)	219-224
Number of pages	6
Journal	CANCER CHEMOTHER.REP.
Volume	57
Issue number	2
State	Published - 1973
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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abstract = "Forty eight patients received vincristine and bleomycin given in sequential combination. Of 32 evaluable patients, nine had a partial response (28%) including four of 15 with lung cancer (27%) and three of nine with head and neck cancer (33%). The results of sequential combination therapy in lung cancer appear to be superior to those previously reported for bleomycin alone. Toxicity of the combination was no greater than that expected of each agent. There was no significant myelosuppression.",

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AU - Gottlieb, J. A.

AU - Frei, E.

PY - 1973

Y1 - 1973

N2 - Forty eight patients received vincristine and bleomycin given in sequential combination. Of 32 evaluable patients, nine had a partial response (28%) including four of 15 with lung cancer (27%) and three of nine with head and neck cancer (33%). The results of sequential combination therapy in lung cancer appear to be superior to those previously reported for bleomycin alone. Toxicity of the combination was no greater than that expected of each agent. There was no significant myelosuppression.

AB - Forty eight patients received vincristine and bleomycin given in sequential combination. Of 32 evaluable patients, nine had a partial response (28%) including four of 15 with lung cancer (27%) and three of nine with head and neck cancer (33%). The results of sequential combination therapy in lung cancer appear to be superior to those previously reported for bleomycin alone. Toxicity of the combination was no greater than that expected of each agent. There was no significant myelosuppression.

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Kinetic scheduling of vincristine (NSC-67574) and bleomycin (NSC-125066) in patients with lung cancer and other malignant tumors

Abstract

ASJC Scopus subject areas

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