@article{6eb98e01b46e4153b2120f1b79e2f0ae,
title = "Kaurane and trachylobane diterpenes from Xylopia aethiopica",
abstract = "Phytochemical investigation of Xylopia aethiopica (Annonaceae) has resulted in the isolation of two novel diterpenes, 15-oxo-(-)-trachyloban-19-oic acid and (-)-kaur-15-en-17-al-19-oic acid. Also encountered were the known compounds 15-hydroxy-(-)-trachyloban-19-oic acid, 15β-hydroxy-(-)-kaur-16-en-19-oic acid (as an inseperable mixture), 15-oxo-(-)-kaur-16-en-19-oic acid and sitosterol glucoside. 13C NMR assignments of 15-hydroxy-(-)- trachyloban-19-oic acid and the assignment of the configuration of its hydroxyl group at C-15 have been carried out for the first time.",
keywords = "Annonaceae, Xylopia aethiopica, kaurane and trachylobane diterpenes, structure elucidation.",
author = "Harrigan, {George G.} and {da S.Bolzani}, Vanderlan and {Leslie Gunatilaka}, {A. A.} and Kingston, {David G.I.}",
note = "Funding Information: Acknowledgements-This work was supported by a National Cooperative Drug Discovery Group awarded to the University of Virginia (I UOl CA 50771)[ Dr S. M. Hecht, Principal Investigator]. We thank SmithKline Beecham Pharmaceuticals for the provision of plant material, Mr Tom E. Glass for 2D NMR spectra, Mr Kim Harich for high resolution mass spectra and MS Nina Baj for expert technical assistance.W e also thank Forestry Enterprises of Ghana through Biotics (U.K.) for the supply of X. uethiopica plant material. One of us (V. da S. B.) acknowledges FAPESP (Fundacao de Amiparo a Pesquisa do Estado de S. Paulo) and UNESP (Uni-versidade Estadual Paulista) for financial support.",
year = "1994",
month = may,
doi = "10.1016/S0031-9422(00)97022-5",
language = "English (US)",
volume = "36",
pages = "109--113",
journal = "Phytochemistry",
issn = "0031-9422",
publisher = "Elsevier Limited",
number = "1",
}