Isotropic diffusion weighting in radial fast spin-echo magnetic resonance imaging

Joelle E. Sarlls, Rexford D. Newbould, Maria I. Altbach, Arthur F. Gmitro, Joachim Seeger, Theodore P. Trouard

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Radial fast spin-echo (radial-FSE) methods enable multishot diffusion-weighted MRI (DWMRI) to be carried out without significant artifacts due to motion and/or susceptibility and can be used to generate DWMRI images with high spatial resolution. In this work, a novel method that allows isotropic diffusion weighting to be obtained in a single radial k-space data set is presented. This is accomplished by altering the direction of diffusion weighting gradients between groups of TR periods, which yield sets of radial lines that possess diffusion weighting sensitive to motion in different directions. By altering the diffusion weighting directions and controlling the view ordering appropriately within the sequence, an effectively isotropic diffusion-weighted image can be obtained within one radial-FSE scan. The order in which radial lines are acquired can also be controlled to yield data sets without significant artifacts due to motion, T2 decay, and/or diffusion anisotropy.

Original languageEnglish (US)
Pages (from-to)1347-1354
Number of pages8
JournalMagnetic Resonance in Medicine
Issue number6
StatePublished - Jun 2005


  • ADC
  • Diffusion
  • MRI
  • Projection reconstruction
  • Radial
  • Stroke

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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