Isosorbide dinitrate oral spray in acute exacerbation of chronic congestive heart failure secondary to coronary artery disease

Alan Marmor; Adam Schneeweiss; Moshe Plich; David Blondheim; Tali Sharir; Joseph S. Alpert

doi:10.1016/0002-9149(87)90876-9

Isosorbide dinitrate oral spray in acute exacerbation of chronic congestive heart failure secondary to coronary artery disease

Alan Marmor, Adam Schneeweiss, Moshe Plich, David Blondheim, Tali Sharir, Joseph S. Alpert

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Lingual and buccal administration of isosorbide dinitrate (ISDN) oral spray is theoretically more rapid in onset of action than sublingual tablet administration because the drug is absorbed from the tablet only after its dissolution. We studied the effect and the pharmacodynamic time course of ISDN spray in patients with acute deterioration of chronic congestive heart failure (CHF).

Original language	English (US)
Pages (from-to)	1199-1200
Number of pages	2
Journal	The American Journal of Cardiology
Volume	59
Issue number	12
DOIs	https://doi.org/10.1016/0002-9149(87)90876-9
State	Published - May 1 1987
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/0002-9149(87)90876-9

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abstract = "Lingual and buccal administration of isosorbide dinitrate (ISDN) oral spray is theoretically more rapid in onset of action than sublingual tablet administration because the drug is absorbed from the tablet only after its dissolution. We studied the effect and the pharmacodynamic time course of ISDN spray in patients with acute deterioration of chronic congestive heart failure (CHF).",

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T1 - Isosorbide dinitrate oral spray in acute exacerbation of chronic congestive heart failure secondary to coronary artery disease

AU - Marmor, Alan

AU - Schneeweiss, Adam

AU - Plich, Moshe

AU - Blondheim, David

AU - Sharir, Tali

AU - Alpert, Joseph S.

PY - 1987/5/1

Y1 - 1987/5/1

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AB - Lingual and buccal administration of isosorbide dinitrate (ISDN) oral spray is theoretically more rapid in onset of action than sublingual tablet administration because the drug is absorbed from the tablet only after its dissolution. We studied the effect and the pharmacodynamic time course of ISDN spray in patients with acute deterioration of chronic congestive heart failure (CHF).

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Isosorbide dinitrate oral spray in acute exacerbation of chronic congestive heart failure secondary to coronary artery disease

Abstract

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