Isolation of a potential antitumor fraction from Rumex hymenosepalus

Jack R. Cole, Leonard Buchalter

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Extracts of Rumex hymenosepalus have shown antitumor activity against the Sarcoma 180 and Walker 256 test systems of the Cancer Chemotherapy National Service Center, Bethesda, Md. The extracts have been fractionated by means of solvent extraction and paper chromatography into two distinct fractions. The partial characterization of these fractions is described, including the characterization of leucocyanidin as one of the constituents and the identification of benzoic acid as a hydrolysis product of a polyphenolic ester.

Original languageEnglish (US)
Pages (from-to)1376-1378
Number of pages3
JournalJournal of pharmaceutical sciences
Issue number9
StatePublished - Sep 1965

ASJC Scopus subject areas

  • Pharmaceutical Science


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