Iron Transport Machinery of Human Cells. Players and Their Interactions

Ningning Zhao, Caroline A. Enns

Research output: Chapter in Book/Report/Conference proceedingChapter

32 Scopus citations


Organisms, like cells, maintain tight control of iron. In humans as well as other mammals, control is achieved through the regulation of iron uptake into the body rather than through the excretion of iron. The mechanisms by which humans and mice regulate both iron uptake and the distribution of iron within the body and cells are reviewed. Special emphasis is given to the iron transporters involved in this process.

Original languageEnglish (US)
Title of host publicationCurrent Topics in Membranes
PublisherAcademic Press Inc.
Number of pages27
StatePublished - 2012
Externally publishedYes

Publication series

NameCurrent Topics in Membranes
ISSN (Print)1063-5823


  • DMT1
  • Ferroportin
  • NRAMP1
  • TRPML1
  • TfR1
  • TfR2
  • Transferrin receptor
  • ZIP14

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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