TY - JOUR
T1 - Intrapulmonary localized fibrous tumor. Intraparenchymal so-called localized fibrous mesothelioma
AU - Yousem, S. A.
AU - Flynn, S. D.
PY - 1988
Y1 - 1988
N2 - This report describes three cases of intrapulmonary fibromas which are histologically identical to localized fibrous tumors of pleura (localized fibrous mesothelioma). Morphologically these tumors are characterized by a haphazard proliferation of cytologically bland spindle cells separated by variable amounts of wavy hyalinized collagen. Entrapped bronchiolar and alveolar epithelium is common. These spindle cells lack expression of cytoplasmic keratin, S-100 protein, desmin, and epithelial membrane antigen, but are strongly decorated for intracellular vimentin. The clinical behavior, differential diagnosis, and histogenesis of these lesions are discussed.
AB - This report describes three cases of intrapulmonary fibromas which are histologically identical to localized fibrous tumors of pleura (localized fibrous mesothelioma). Morphologically these tumors are characterized by a haphazard proliferation of cytologically bland spindle cells separated by variable amounts of wavy hyalinized collagen. Entrapped bronchiolar and alveolar epithelium is common. These spindle cells lack expression of cytoplasmic keratin, S-100 protein, desmin, and epithelial membrane antigen, but are strongly decorated for intracellular vimentin. The clinical behavior, differential diagnosis, and histogenesis of these lesions are discussed.
UR - https://www.scopus.com/pages/publications/0023915844
UR - https://www.scopus.com/pages/publications/0023915844#tab=citedBy
U2 - 10.1093/ajcp/89.3.365
DO - 10.1093/ajcp/89.3.365
M3 - Article
C2 - 2450451
AN - SCOPUS:0023915844
SN - 0002-9173
VL - 89
SP - 365
EP - 369
JO - American journal of clinical pathology
JF - American journal of clinical pathology
IS - 3
ER -