INTRAPORTAL INSULIN PROTECTS FROM THE LIVER INJURY OF PORTACAVAL SHUNT IN DOGS

Thomas E. Starzl, Kendrick A. Porter, Charles W. Putnam

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

4 days after portacaval shunt, the livers of normal dogs had pronounced atrophy and other structural abnormalities. These changes were greatly reduced in the left liver lobes, but not in the right, by a constant infusion to the left portal vein of insulin in non-hypoglycæmic doses. These experimental findings should have implications in clinical medicine.

Original languageEnglish (US)
Pages (from-to)1241-1242
Number of pages2
JournalThe Lancet
Volume306
Issue number7947
DOIs
StatePublished - Dec 20 1975
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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