Intraperitoneal chemotherapy: Technical experience at five institutions

Martine J. Piccart, James L. Speyer, Maurie Markman, WW ten Bokkel Huinink, David Alberts, Jean Jenkins, Franco Muggia

Research output: Contribution to journalArticlepeer-review

96 Scopus citations


With the rapid expansion of research programs examining intraperitoneal chemotherapy for ovarian cancer and other intraabdominal malignancies, there is a need for a reliable and safe access to the peritoneal cavity. The technical experience accumulated with either the Tenckhoff catheter or the Port-A-Cath in 288 patients treated at five institutions showed a low incidence of catheter-related peritonitis (5% and 8%, respectively), skin infection (6.6% and 0%), and bowel perforation following surgical implantation (3.5% and 1.3%). Postoperative leakage of intraabdominal fluid, bleeding, or ileus were uncommon and easily controlled. Drainage failure was the major problem with both systems; occurring in 45% of patients. Although both systems are workable, improved catheters for the administration of intraperitoneal chemotherapy are warranted.

Original languageEnglish (US)
Pages (from-to)90-96
Number of pages7
JournalSeminars in Oncology
Issue number3 SUPPL. 4
StatePublished - Sep 1985

ASJC Scopus subject areas

  • Hematology
  • Oncology


Dive into the research topics of 'Intraperitoneal chemotherapy: Technical experience at five institutions'. Together they form a unique fingerprint.

Cite this