Intraoperative discovery of neuroblastoma in an infant with pulmonary atresia

Doff B. McElhinney, V. Mohan Reddy, Burt G. Feuerstein, Gerald R. Marx, Frank L. Hanley

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


There have been 28 previously reported cases of neuroblastoma associated with congenital heart disease. Because many of these have been defects of the conotruncal region, it has been proposed that abnormal neural crest cell migration or maturation may be a factor that links these normally disparate pathologic conditions. Most neuroblastomas in these cases have been detected at autopsy or by radiologic studies conducted in the evaluation of the cardiac anomalies. Recently, we discovered an occult posterior mediastinal neuroblastoma in a patient undergoing a unifocalization procedure for tetralogy of Fallot with pulmonary atresia and major aortopulmonary collaterals. The tumor was resected, and the patient has demonstrated no evidence of residual or metastatic neuroblastoma.

Original languageEnglish (US)
Pages (from-to)1827-1829
Number of pages3
JournalAnnals of Thoracic Surgery
Issue number6
StatePublished - Dec 1997

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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