@article{355862f51848409f8136aff24ddb68e5,
title = "Interim estimates of vaccine effectiveness of BNT162b2 and mRNA-1273 COVID-19 vaccines in preventing SARS-CoV-2 infection among health care personnel, first responders, and other essential and frontline workers Eight U.S. Locations, December 2020 March 2021",
abstract = "What is already known about this topic? Messenger RNA (mRNA) COVID-19 vaccines have been shown to be effective in preventing symptomatic SARS-CoV-2 infection in randomized placebo-controlled Phase III trials. What is added by this report? Prospective cohorts of 3,950 health care personnel, first responders, and other essential and frontline workers completed weekly SARS-CoV-2 testing for 13 consecutive weeks. Under real-world conditions, mRNA vaccine effectiveness of full immunization (≥14 days after second dose) was 90% against SARS-CoV-2 infections regardless of symptom status; vaccine effectiveness of partial immunization (≥14 days after first dose but before second dose) was 80%. What are the implications for public health practice? Authorized mRNA COVID-19 vaccines are effective for preventing SARS-CoV-2 infection in real-world conditions. COVID-19 vaccination is recommended for all eligible persons.",
author = "Thompson, {Mark G.} and Burgess, {Jefferey L.} and Naleway, {Allison L.} and Tyner, {Harmony L.} and Yoon, {Sarang K.} and Jennifer Meece and Olsho, {Lauren E.W.} and Caban-Martinez, {Alberto J.} and Ashley Fowlkes and Karen Lutrick and Kuntz, {Jennifer L.} and Kayan Dunnigan and Odean, {Marilyn J.} and Hegmann, {Kurt T.} and Elisha Stefanski and Edwards, {Laura J.} and Natasha Schaefer-Solle and Lauren Grant and Katherine Ellingson and Groom, {Holly C.} and Tnelda Zunie and Thiese, {Matthew S.} and Lynn Ivacic and Wesley, {Meredith G.} and Lamberte, {Julie Mayo} and Xiaoxiao Sun and Smith, {Michael E.} and Phillips, {Andrew L.} and Groover, {Kimberly D.} and Yoo, {Young M.} and Joe Gerald and Brown, {Rachel T.} and Herring, {Meghan K.} and Gregory Joseph and Shawn Beitel and Morrill, {Tyler C.} and Josephine Mak and Patrick Rivers and Harris, {Katherine M.} and Hunt, {Danielle R.} and Arvay, {Melissa L.} and Preeta Kutty and Fry, {Alicia M.} and Manjusha Gaglani",
note = "Publisher Copyright: {\textcopyright} 2021 Department of Health and Human Services. All rights reserved.",
year = "2021",
doi = "10.15585/MMWR.MM7013E3",
language = "English (US)",
volume = "70",
pages = "495--500",
journal = "Morbidity and Mortality Weekly Report",
issn = "0149-2195",
publisher = "Department of Health and Human Services",
number = "13",
}