Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021

Karen Lutrick; Patrick Rivers; Young M. Yoo; Lauren Grant; James Hollister; Krystal Jovel; Sana Khan; Ashley Lowe; Zoe Baccam; Hanna Hanson; Lauren E.W. Olsho; Ashley Fowlkes; Alberto J. Caban-Martinez; Cynthia Porter; Sarang Yoon; Jennifer Meece; Manjusha Gaglani; Joy Burns; Julie Mayo Lamberte; Flavia Nakayima Miiro; Adam Bissonnette; Lindsay LeClair; Preeta K. Kutty; James K. Romine; Elisha Stefanski; Laura J. Edwards; Katherine Ellingson; Joe K. Gerald; Edward J. Bedrick; Purnima Madhivanan; Karl Krupp; Lynn B. Gerald; Mark Thompson; Jefferey L. Burgess

doi:10.15585/MMWR.MM705152A2

Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021

Karen Lutrick, Patrick Rivers, Young M. Yoo, Lauren Grant, James Hollister, Krystal Jovel, Sana Khan, Ashley Lowe, Zoe Baccam, Hanna Hanson, Lauren E.W. Olsho, Ashley Fowlkes, Alberto J. Caban-Martinez, Cynthia Porter, Sarang Yoon, Jennifer Meece, Manjusha Gaglani, Joy Burns, Julie Mayo Lamberte, Flavia Nakayima MiiroAdam Bissonnette, Lindsay LeClair, Preeta K. Kutty, James K. Romine, Elisha Stefanski, Laura J. Edwards, Katherine Ellingson, Joe K. Gerald, Edward J. Bedrick, Purnima Madhivanan, Karl Krupp, Lynn B. Gerald, Mark Thompson, Jefferey L. Burgess

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

What is already known about this topic? The Pfizer-BioNTech COVID-19 vaccine has been shown to be effective in preventing SARS-CoV-2 infection in adolescents in randomized placebo-controlled Phase III trials. What is added by this report? A prospective cohort of 243 adolescents aged 12–17 years in Arizona completed weekly SARS-CoV-2 testing by nasal swab for 19 consecutive weeks. Under real-world conditions, vaccine effectiveness of full immunization (completion of the second in a 2-dose series ≥14 days earlier) was 92% against SARS-CoV-2 infections irrespective of symptom status. What are the implications for public health practice? In real-world conditions among adolescents aged 12–17 years, the Pfizer-BioNTech vaccine was highly effective in preventing SARS-CoV-2 infection.

Original language	English (US)
Pages (from-to)	1761-1765
Number of pages	5
Journal	Morbidity and Mortality Weekly Report
Volume	70
Issue number	5152
DOIs	https://doi.org/10.15585/MMWR.MM705152A2
State	Published - 2021

ASJC Scopus subject areas

Epidemiology
Health(social science)
Health, Toxicology and Mutagenesis
Health Information Management

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10.15585/MMWR.MM705152A2

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Lutrick, K., Rivers, P., Yoo, Y. M., Grant, L., Hollister, J., Jovel, K., Khan, S., Lowe, A., Baccam, Z., Hanson, H., Olsho, L. E. W., Fowlkes, A., Caban-Martinez, A. J., Porter, C., Yoon, S., Meece, J., Gaglani, M., Burns, J., Lamberte, J. M., ... Burgess, J. L. (2021). Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021. Morbidity and Mortality Weekly Report, 70(5152), 1761-1765. https://doi.org/10.15585/MMWR.MM705152A2

Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021. / Lutrick, Karen; Rivers, Patrick; Yoo, Young M. et al.
In: Morbidity and Mortality Weekly Report, Vol. 70, No. 5152, 2021, p. 1761-1765.

Research output: Contribution to journal › Article › peer-review

Lutrick, K, Rivers, P, Yoo, YM, Grant, L, Hollister, J, Jovel, K, Khan, S, Lowe, A, Baccam, Z, Hanson, H, Olsho, LEW, Fowlkes, A, Caban-Martinez, AJ, Porter, C, Yoon, S, Meece, J, Gaglani, M, Burns, J, Lamberte, JM, Miiro, FN, Bissonnette, A, LeClair, L, Kutty, PK, Romine, JK, Stefanski, E, Edwards, LJ, Ellingson, K , Gerald, JK , Bedrick, EJ , Madhivanan, P, Krupp, K, Gerald, LB, Thompson, M & Burgess, JL 2021, 'Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021', Morbidity and Mortality Weekly Report, vol. 70, no. 5152, pp. 1761-1765. https://doi.org/10.15585/MMWR.MM705152A2

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title = "Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021",

abstract = "What is already known about this topic? The Pfizer-BioNTech COVID-19 vaccine has been shown to be effective in preventing SARS-CoV-2 infection in adolescents in randomized placebo-controlled Phase III trials. What is added by this report? A prospective cohort of 243 adolescents aged 12–17 years in Arizona completed weekly SARS-CoV-2 testing by nasal swab for 19 consecutive weeks. Under real-world conditions, vaccine effectiveness of full immunization (completion of the second in a 2-dose series ≥14 days earlier) was 92% against SARS-CoV-2 infections irrespective of symptom status. What are the implications for public health practice? In real-world conditions among adolescents aged 12–17 years, the Pfizer-BioNTech vaccine was highly effective in preventing SARS-CoV-2 infection.",

author = "Karen Lutrick and Patrick Rivers and Yoo, {Young M.} and Lauren Grant and James Hollister and Krystal Jovel and Sana Khan and Ashley Lowe and Zoe Baccam and Hanna Hanson and Olsho, {Lauren E.W.} and Ashley Fowlkes and Caban-Martinez, {Alberto J.} and Cynthia Porter and Sarang Yoon and Jennifer Meece and Manjusha Gaglani and Joy Burns and Lamberte, {Julie Mayo} and Miiro, {Flavia Nakayima} and Adam Bissonnette and Lindsay LeClair and Kutty, {Preeta K.} and Romine, {James K.} and Elisha Stefanski and Edwards, {Laura J.} and Katherine Ellingson and Gerald, {Joe K.} and Bedrick, {Edward J.} and Purnima Madhivanan and Karl Krupp and Gerald, {Lynn B.} and Mark Thompson and Burgess, {Jefferey L.}",

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AU - Rivers, Patrick

AU - Yoo, Young M.

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AU - Lamberte, Julie Mayo

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AU - Bissonnette, Adam

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AU - Kutty, Preeta K.

AU - Romine, James K.

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AU - Edwards, Laura J.

AU - Ellingson, Katherine

AU - Gerald, Joe K.

AU - Bedrick, Edward J.

AU - Madhivanan, Purnima

AU - Krupp, Karl

AU - Gerald, Lynn B.

AU - Thompson, Mark

AU - Burgess, Jefferey L.

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Interim Estimate of Vaccine Effectiveness of BNT162b2 (Pfizer-BioNTech) Vaccine in Preventing SARS-CoV-2 Infection Among Adolescents Aged 12–17 Years — Arizona, July–December 2021

Abstract

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