Integration and Testing of the Hybrid Gamma Cameras for AdaptiSPECT-C

R. Garrett Richards, Maria Ruiz-Gonzalez, Kimberly J. Doty, Benjamin Auer, Matthew A. Kupinski, Michael A. King, Phillip H. Kuo, Lars R. Furenlid

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recent advances in scintillation light sensors are enabling new designs for single-photon-emission computed tomography (SPECT) cameras for use in nuclear medicine, achieving higher sensitivity and spatial resolution than previously possible. One such camera is AdaptiSPECT-C: a new stationary and adaptive SPECT system designed for clinical whole-brain imaging. It employs a 24-stationary-camera configuration in conjunction with multi-pinhole apertures, significantly increasing its overall sensitivity to gamma radiation. Each of the five pinholes assigned to a camera can actively select among several different aperture diameters and a shuttered state; the latter function enabling the acquisition of both non-multiplexed and multiplexed image data in a single session.Each 18-cm-square camera in AdaptiSPECT-C houses 25 photomultiplier tubes (PMTs) and 24 multi-pixel photon counters (MPPCs). This combination results in a camera that achieves uniformly high spatial resolution across the entire crystal area. In this work we present the combined MPPC/PMT hybrid camera design, prioritizing modularity and space efficiency. We also cover schematics for the front-end electronics and their hardware integration, specifically highlighting initial test pulses from the two sensor types. The results of said testing show promise for the eventual merging of hybrid signal information into a comprehensive dataset during real world image acquisitions. Finally, we present preliminary calibration results and compare to predictions based on light-transport simulations.

Original languageEnglish (US)
Title of host publication2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022
EditorsHideki Tomita, Tatsuya Nakamura
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665421133
DOIs
StatePublished - 2021
Event2021 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2021 - Virtual, Yokohama, Japan
Duration: Oct 16 2021Oct 23 2021

Publication series

Name2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022

Conference

Conference2021 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2021
Country/TerritoryJapan
CityVirtual, Yokohama
Period10/16/2110/23/21

Keywords

  • SPECT
  • SiPMs
  • gamma-ray detectors
  • molecular imaging
  • silicon photomultipliers

ASJC Scopus subject areas

  • Nuclear Energy and Engineering
  • Health Informatics
  • Radiology Nuclear Medicine and imaging
  • Nuclear and High Energy Physics

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