Intérêt des marqueurs sanguins dans la prédiction de la toxicité radio-induite

Translated title of the contribution: Interest of blood markers in predicting radiation-induced toxicity

J. Lacombe, J. Solassol, M. Coelho, M. Ozsahin, D. Azria

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations


The oncologic outcome and the total dose are highly correlated with the treatment by ionizing radiation. The dose increase (total or per fraction) may provoke late-side effects that are potentially irreversible. The radiation-induced CD8 lymphocyte apoptotic value and the molecular modifications within the lymphocyte are capable of predicting the level of risk of developing late-side effects after curative intent radiotherapy. In this review, we present the different blood assays in this setting and discuss the current possibilities of researches, namely those involving the proteomic process.

Translated title of the contributionInterest of blood markers in predicting radiation-induced toxicity
Original languageFrench
Pages (from-to)390-393
Number of pages4
JournalCancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Issue number5
StatePublished - Aug 2011
Externally publishedYes


  • Proteomic
  • Radiotherapy
  • Toxicity

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging


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