Inhibition of DNA transcription elongation and unwinding by bis-PNA

L. Bastide; G. Villani; P. Nielsen; P. E. Boehmer; B. Lebleu

doi:10.1080/07328319908044818

Inhibition of DNA transcription elongation and unwinding by bis-PNA

L. Bastide, G. Villani, P. Nielsen, P. E. Boehmer, B. Lebleu

Research output: Contribution to journal › Article › peer-review

Abstract

The possibility to arrest transcription elongation by bis-PNA has been investigated. No arrest of transcription has been obtained in intact cells at variance with the data observed with purified RNA-polymerases. In keeping with these data a purified DNA-helicase (UL9) cannot be fully inhibited by such complexes.

Original language	English (US)
Pages (from-to)	1669-1671
Number of pages	3
Journal	Nucleosides and Nucleotides
Volume	18
Issue number	6-7
DOIs	https://doi.org/10.1080/07328319908044818
State	Published - 1999
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Genetics

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10.1080/07328319908044818

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title = "Inhibition of DNA transcription elongation and unwinding by bis-PNA",

abstract = "The possibility to arrest transcription elongation by bis-PNA has been investigated. No arrest of transcription has been obtained in intact cells at variance with the data observed with purified RNA-polymerases. In keeping with these data a purified DNA-helicase (UL9) cannot be fully inhibited by such complexes.",

author = "L. Bastide and G. Villani and P. Nielsen and Boehmer, {P. E.} and B. Lebleu",

year = "1999",

doi = "10.1080/07328319908044818",

language = "English (US)",

volume = "18",

pages = "1669--1671",

journal = "Nucleosides and Nucleotides",

issn = "0732-8311",

publisher = "Marcel Dekker Inc.",

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T1 - Inhibition of DNA transcription elongation and unwinding by bis-PNA

AU - Bastide, L.

AU - Villani, G.

AU - Nielsen, P.

AU - Boehmer, P. E.

AU - Lebleu, B.

PY - 1999

Y1 - 1999

N2 - The possibility to arrest transcription elongation by bis-PNA has been investigated. No arrest of transcription has been obtained in intact cells at variance with the data observed with purified RNA-polymerases. In keeping with these data a purified DNA-helicase (UL9) cannot be fully inhibited by such complexes.

AB - The possibility to arrest transcription elongation by bis-PNA has been investigated. No arrest of transcription has been obtained in intact cells at variance with the data observed with purified RNA-polymerases. In keeping with these data a purified DNA-helicase (UL9) cannot be fully inhibited by such complexes.

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U2 - 10.1080/07328319908044818

DO - 10.1080/07328319908044818

M3 - Article

AN - SCOPUS:0032800751

SN - 0732-8311

VL - 18

SP - 1669

EP - 1671

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 6-7

ER -

Inhibition of DNA transcription elongation and unwinding by bis-PNA

Abstract

ASJC Scopus subject areas

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