Abstract
Cathepsin G stimulates the hydrolysis of elastin from bovine neck ligament catalyzed by human leukocyte elastase. Stimulation factor depends on the ratio of the enzyme concentrations and ionic strength and equals 1.0-2.0. The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and the mixture of both. The inhibitory effect is practically unaffected by the adsorption of the enzymes on elastin, prolongation of the enzymatic reaction and ionic strength.
Translated title of the contribution | Inhibition of elastin hydrolysis, catalyzed by human leukocyte elastase and cathepsin G, by the Bowman-Birk type soy inhibitor |
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Original language | Russian |
Pages (from-to) | 1739-1745 |
Number of pages | 7 |
Journal | Biokhimiya |
Volume | 59 |
Issue number | 11 |
State | Published - Nov 1994 |
Externally published | Yes |
ASJC Scopus subject areas
- General Chemistry