Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka.

Translated title of the contribution: Inhibition of elastin hydrolysis, catalyzed by human leukocyte elastase and cathepsin G, by the Bowman-Birk type soy inhibitor

T. V. Tikhonova, I. P. Gladysheva, N. F. Kazanskaia, N. I. Larionova

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Cathepsin G stimulates the hydrolysis of elastin from bovine neck ligament catalyzed by human leukocyte elastase. Stimulation factor depends on the ratio of the enzyme concentrations and ionic strength and equals 1.0-2.0. The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and the mixture of both. The inhibitory effect is practically unaffected by the adsorption of the enzymes on elastin, prolongation of the enzymatic reaction and ionic strength.

Translated title of the contributionInhibition of elastin hydrolysis, catalyzed by human leukocyte elastase and cathepsin G, by the Bowman-Birk type soy inhibitor
Original languageRussian
Pages (from-to)1739-1745
Number of pages7
JournalBiokhimiya
Volume59
Issue number11
StatePublished - Nov 1994
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry

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