TY - JOUR
T1 - Influence of Malnutrition on the Concentration of IgA, Lysozyme, Amylase, and Aminopeptidase in Children's Tears
AU - Watson, Ronald R.
AU - Reyes, Marco A.
AU - Mcmurray, David N.
N1 - Funding Information:
This study was supported by U.S. Public Health Service Grants HD-09098 and AI-10050, by the National Livestock and Meat Board, the Research Corporation, and by the Tulane University-International Center for Medical Research, Cali, Colombia.
PY - 1978/2
Y1 - 1978/2
N2 - Sixty-four pre-school-age children from a poor urban population in Colombia were studied to determine the influence of moderate to severe malnutrition on several proteins in the serum and tears. Secretory IgA, lysozyme, and amylase were found in significantly reduced concentrations in the tears of malnourished children. No influence of nutritional status on total proteins, albumin, and aminopeptidase was observed in this secretion. In the serum, IgA concentrations were significantly higher in the most malnourished group, while total proteins and albumin were reduced. These data suggest that increased susceptibility to infections of mucosal surfaces in malnourished children may be due to reduced concentrations of protective substances such as IgA and lysozyme in secretions.
AB - Sixty-four pre-school-age children from a poor urban population in Colombia were studied to determine the influence of moderate to severe malnutrition on several proteins in the serum and tears. Secretory IgA, lysozyme, and amylase were found in significantly reduced concentrations in the tears of malnourished children. No influence of nutritional status on total proteins, albumin, and aminopeptidase was observed in this secretion. In the serum, IgA concentrations were significantly higher in the most malnourished group, while total proteins and albumin were reduced. These data suggest that increased susceptibility to infections of mucosal surfaces in malnourished children may be due to reduced concentrations of protective substances such as IgA and lysozyme in secretions.
UR - http://www.scopus.com/inward/record.url?scp=0017844610&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017844610&partnerID=8YFLogxK
U2 - 10.3181/00379727-157-40024
DO - 10.3181/00379727-157-40024
M3 - Article
C2 - 414236
AN - SCOPUS:0017844610
SN - 0037-9727
VL - 157
SP - 215
EP - 219
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
IS - 2
ER -