Influence of hydroxypropyl-β-cyclodextrin (HPCD) on the bioavailability and biodegradation of pyrene

Jiann Ming Wang; Raina M. Maier; Mark L. Brusseau

doi:10.1016/j.chemosphere.2005.03.031

Influence of hydroxypropyl-β-cyclodextrin (HPCD) on the bioavailability and biodegradation of pyrene

Jiann Ming Wang, Raina M. Maier, Mark L. Brusseau

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

It is well known that the limited aqueous solubilities of polycyclic aromatic hydrocarbons (PAH) often reduce their bioavailability to bacterial populations. The objective of this study was to test the impact of a solubility-enhancement reagent, hydroxypropyl-β-cyclodextrin (HPCD), on the bioavailability and biodegradation of pyrene. No measurable loss of pyrene occurred for the control vials throughout the first 22 weeks of the experiment, indicating the absence of mass loss via abiotic transformation and volatilization. The vials containing pyrene and the degrader isolate (Burkholderia CRE 7), but no HPCD, also exhibited no measurable loss of pyrene throughout the experiment. Conversely, biodegradation of pyrene appears to have been initiated after approximately 15 weeks for the vials containing 10 ⁴ mg l^-1 HPCD. By the end of the experiment, approximately 14% (w/w) of the pyrene was biodegraded in the presence of HPCD. These results indicate that HPCD may be useful for enhancing the bioavailability and biodegradation of pyrene and other PAHs.

Original language	English (US)
Pages (from-to)	725-728
Number of pages	4
Journal	Chemosphere
Volume	60
Issue number	5
DOIs	https://doi.org/10.1016/j.chemosphere.2005.03.031
State	Published - Jul 2005

ASJC Scopus subject areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Health, Toxicology and Mutagenesis

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10.1016/j.chemosphere.2005.03.031

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title = "Influence of hydroxypropyl-β-cyclodextrin (HPCD) on the bioavailability and biodegradation of pyrene",

abstract = "It is well known that the limited aqueous solubilities of polycyclic aromatic hydrocarbons (PAH) often reduce their bioavailability to bacterial populations. The objective of this study was to test the impact of a solubility-enhancement reagent, hydroxypropyl-β-cyclodextrin (HPCD), on the bioavailability and biodegradation of pyrene. No measurable loss of pyrene occurred for the control vials throughout the first 22 weeks of the experiment, indicating the absence of mass loss via abiotic transformation and volatilization. The vials containing pyrene and the degrader isolate (Burkholderia CRE 7), but no HPCD, also exhibited no measurable loss of pyrene throughout the experiment. Conversely, biodegradation of pyrene appears to have been initiated after approximately 15 weeks for the vials containing 10 4 mg l-1 HPCD. By the end of the experiment, approximately 14% (w/w) of the pyrene was biodegraded in the presence of HPCD. These results indicate that HPCD may be useful for enhancing the bioavailability and biodegradation of pyrene and other PAHs.",

author = "Wang, {Jiann Ming} and Maier, {Raina M.} and Brusseau, {Mark L.}",

note = "Funding Information: This research was supported by the National Institute of Environmental Health Sciences Superfund Basic Research Program, NIH Grant number 2P42ES04940-11.",

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AU - Maier, Raina M.

AU - Brusseau, Mark L.

N1 - Funding Information: This research was supported by the National Institute of Environmental Health Sciences Superfund Basic Research Program, NIH Grant number 2P42ES04940-11.

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Y1 - 2005/7

N2 - It is well known that the limited aqueous solubilities of polycyclic aromatic hydrocarbons (PAH) often reduce their bioavailability to bacterial populations. The objective of this study was to test the impact of a solubility-enhancement reagent, hydroxypropyl-β-cyclodextrin (HPCD), on the bioavailability and biodegradation of pyrene. No measurable loss of pyrene occurred for the control vials throughout the first 22 weeks of the experiment, indicating the absence of mass loss via abiotic transformation and volatilization. The vials containing pyrene and the degrader isolate (Burkholderia CRE 7), but no HPCD, also exhibited no measurable loss of pyrene throughout the experiment. Conversely, biodegradation of pyrene appears to have been initiated after approximately 15 weeks for the vials containing 10 4 mg l-1 HPCD. By the end of the experiment, approximately 14% (w/w) of the pyrene was biodegraded in the presence of HPCD. These results indicate that HPCD may be useful for enhancing the bioavailability and biodegradation of pyrene and other PAHs.

AB - It is well known that the limited aqueous solubilities of polycyclic aromatic hydrocarbons (PAH) often reduce their bioavailability to bacterial populations. The objective of this study was to test the impact of a solubility-enhancement reagent, hydroxypropyl-β-cyclodextrin (HPCD), on the bioavailability and biodegradation of pyrene. No measurable loss of pyrene occurred for the control vials throughout the first 22 weeks of the experiment, indicating the absence of mass loss via abiotic transformation and volatilization. The vials containing pyrene and the degrader isolate (Burkholderia CRE 7), but no HPCD, also exhibited no measurable loss of pyrene throughout the experiment. Conversely, biodegradation of pyrene appears to have been initiated after approximately 15 weeks for the vials containing 10 4 mg l-1 HPCD. By the end of the experiment, approximately 14% (w/w) of the pyrene was biodegraded in the presence of HPCD. These results indicate that HPCD may be useful for enhancing the bioavailability and biodegradation of pyrene and other PAHs.

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Influence of hydroxypropyl-β-cyclodextrin (HPCD) on the bioavailability and biodegradation of pyrene

Abstract

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