Induction of the proto-oncogene c-jun by angiotensin II

A. J. Naftilan; G. K. Gilliland; C. S. Eldridge; A. S. Kraft

doi:10.1128/MCB.10.10.5536

Induction of the proto-oncogene c-jun by angiotensin II

A. J. Naftilan, G. K. Gilliland, C. S. Eldridge, A. S. Kraft

Research output: Contribution to journal › Article › peer-review

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Abstract

Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.

Original language	English (US)
Pages (from-to)	5536-5540
Number of pages	5
Journal	Molecular and cellular biology
Volume	10
Issue number	10
DOIs	https://doi.org/10.1128/MCB.10.10.5536
State	Published - 1990

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1128/MCB.10.10.5536

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title = "Induction of the proto-oncogene c-jun by angiotensin II",

abstract = "Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.",

author = "Naftilan, {A. J.} and Gilliland, {G. K.} and Eldridge, {C. S.} and Kraft, {A. S.}",

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AB - Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.

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Induction of the proto-oncogene c-jun by angiotensin II

Abstract

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