Indoor inhalation intake fractions of fine particulate matter: review of influencing factors

N. Hodas, M. Loh, H. M. Shin, D. Li, D. Bennett, T. E. McKone, O. Jolliet, C. J. Weschler, M. Jantunen, P. Lioy, P. Fantke

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations


Exposure to fine particulate matter (PM2.5) is a major contributor to the global human disease burden. The indoor environment is of particular importance when considering the health effects associated with PM2.5 exposures because people spend the majority of their time indoors and PM2.5 exposures per unit mass emitted indoors are two to three orders of magnitude larger than exposures to outdoor emissions. Variability in indoor PM2.5 intake fraction (iFin,total), which is defined as the integrated cumulative intake of PM2.5 per unit of emission, is driven by a combination of building-specific, human-specific, and pollutant-specific factors. Due to a limited availability of data characterizing these factors, however, indoor emissions and intake of PM2.5 are not commonly considered when evaluating the environmental performance of product life cycles. With the aim of addressing this barrier, a literature review was conducted and data characterizing factors influencing iFin,total were compiled. In addition to providing data for the calculation of iFin,total in various indoor environments and for a range of geographic regions, this paper discusses remaining limitations to the incorporation of PM2.5-derived health impacts into life cycle assessments and makes recommendations regarding future research.

Original languageEnglish (US)
Pages (from-to)836-856
Number of pages21
JournalIndoor Air
Issue number6
StatePublished - Dec 1 2016


  • Fine particulate matter
  • Human exposure
  • Indoor air
  • Intake fraction
  • Life cycle impact assessment
  • Ventilation

ASJC Scopus subject areas

  • Environmental Engineering
  • Building and Construction
  • Public Health, Environmental and Occupational Health


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