Indicators of symptom improvement and survival in inpatients with advanced cancer undergoing palliative surgical consultation

Brian D. Badgwell, Thomas A. Aloia, John Garrett, Gabe Chedister, Tom Miner, Robert Krouse

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Background The purpose of this study was to prospectively identify the presentation, treatment, and outcomes of inpatients with advanced malignancy undergoing palliative surgical consultation. Methods Inpatients undergoing palliative surgical consultation were prospectively identified from November 2008 to May 2011. Medical records were retrospectively reviewed to obtain clinical data and outcome. Results Of 202 consultations, the diagnoses were wound problems (N = 39, 19%), bowel obstruction (N = 75, 37%), intra-abdominal inflammatory conditions (N = 36, 18%), abdominal pain of unclear etiology (N = 13, 6%), gastrointestinal hemorrhage (N = 15, 7%), malnutrition/feeding tube request (N = 14, 7%), and biliary obstruction (N = 10, 5%). Management included non-operative/non-procedural treatment in 81 (40%), procedures in 35 (17%), and surgery in 86 (43%). Patients treated with non-operative/non-procedural, procedural, and surgical treatment demonstrated symptom improvement rates of 60% (49/81), 69% (24/35), and 78% (67/86), respectively. Surgical treatment was associated with symptom improvement (OR 2.3 [95% CI 1.2-4.5]) compared to non-operative/non-procedural management. Symptom improvement was associated with improved survival (HR 0.27 [95% CI 0.19-0.38]) on multivariate analysis. Conclusions Symptom improvement was obtained in the majority of patients regardless of treatment strategy. Although patients selected for surgery demonstrated an association with symptom improvement, future prospective studies are needed to determine additional variables important in treatment selection.

Original languageEnglish (US)
Pages (from-to)367-371
Number of pages5
JournalJournal of Surgical Oncology
Issue number4
StatePublished - Mar 2013


  • advanced cancer
  • palliative care
  • surgery
  • surgical oncology

ASJC Scopus subject areas

  • Surgery
  • Oncology


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