Incidence and pathogen distribution of healthcare-associated infections in pilot hospitals in Egypt

Isaac See, Fernanda C. Lessa, Omar Abo Elata, Soad Hafez, Karim Samy, Amani El-Kholy, Mervat Gaber El Anani, Ghada Ismail, Amr Kandeel, Ramy Galal, Katherine Ellingson, Maha Talaat

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

objective. To report type and rates of healthcare-associated infections (HAIs) as well as pathogen distribution and antimicrobial resistance patterns from a pilot HAI surveillance system in Egypt. methods. Prospective surveillance was conducted from April 2011 through March 2012 in 46 intensive care units (ICUs) in Egypt. Definitions were adapted from the Centers for Disease Control and Prevention's National Healthcare Safety Network. Trained healthcare workers identified HAIs and recorded data on clinical symptoms and up to 4 pathogens. A convenience sample of clinical isolates was tested for antimicrobial resistance at a central reference laboratory. Multidrug resistance was defined by international consensus criteria. results. ICUs from 11 hospitals collected 90,515 patient-days of surveillance data. Of 472 HAIs identified, 47% were pneumonia, 22% were bloodstream infections, and 15% were urinary tract infections; case fatality among HAI case patients was 43%. The highest rate of device-associated infections was reported for ventilator-associated pneumonia (pooled mean rate, 7.47 cases per 1,000 ventilator-days). The most common pathogens reported were Acinetobacter species (21.8%) and Klebsiella species (18.4%). All Acinetobacter isolates tested (31/31) were multidrug resistant, and 71% (17/24) of Klebsiella pneumoniae isolates were extended-spectrum b-lactamase producers. conclusions. Infection control priorities in Egypt should include preventing pneumonia and preventing infections due to antimicrobialresistant pathogens.

Original languageEnglish (US)
Pages (from-to)1281-1288
Number of pages8
JournalInfection Control and Hospital Epidemiology
Volume34
Issue number12
DOIs
StatePublished - Dec 2013
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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