Abstract
A male infant infected in utero with Epstein-Barr virus (EBV) demonstrated a syndrome of multiple congenital anomalies (micrognathia, cryptorchidism, central cataracts), hypotonia, thrombocytopenia, persistent monocytosis, proteinuria, and multiple areas of metaphysitis at birth. Lymphocytes were Epstein-Barr nuclear antigen (EBNA) positive (18%) and persisted in culture for three months. He had antibody to early antigen (anti-EA), IgM-viral capsid (anti VCA), and EBNA (anti-EBNA) detectable at 22 days of age. All attempts to isolate infectious agents or to serologically identify other infectious causes for this syndrome were negative.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1579-1581 |
| Number of pages | 3 |
| Journal | Journal of the American Medical Association |
| Volume | 246 |
| Issue number | 14 |
| DOIs | |
| State | Published - Nov 13 1981 |
ASJC Scopus subject areas
- General Medicine
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