Improved synthesis of d,l-fluorocitric acid

Ruben Vardanyan, Vlad K. Kumirov, Victor J. Hruby

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


We propose a decagram synthesis of commercially unavailable fluorocitric acid. The synthesis begins with benzyl fluoroacetate, which is converted to dibenzyl 2-fluoro-3-oxosuccinate, followed by condensation with malonic acid or its monobenzyl ester and subsequent hydrogenolysis.

Original languageEnglish (US)
Pages (from-to)920-924
Number of pages5
JournalJournal of Fluorine Chemistry
Issue number11
StatePublished - Nov 2011
Externally publishedYes


  • Fluorocitric acid

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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