Implications of the universal definition of myocardial infarction

Joseph S. Alpert, Kristian Thygesen, Harvey D. White, Allan S. Jaffe

Research output: Contribution to journalComment/debatepeer-review

13 Scopus citations


The original WHO definition of myocardial infarction (MI) was revised in 2000 and further refined in 2007. Central to the new universal definition of MI was the use of the highly sensitive and specific biomarker troponin. In the investigation reviewed in this commentary, Hochholzer et al. showed that acute and long-term postinfarction prognosis and mortality were adversely affected when patients met the newly revised criteria for acute MI.

Original languageEnglish (US)
Pages (from-to)678-679
Number of pages2
JournalNature Clinical Practice Cardiovascular Medicine
Issue number11
StatePublished - 2008

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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