Impact of Patient Navigation Interventions on Timely Diagnostic Follow Up for Abnormal Cervical Screening

Electra D. Paskett, Donald Dudley, Gregory S. Young, Brittany M. Bernardo, Kristen J. Wells, Elizabeth A. Calhoun, Kevin Fiscella, Steven R. Patierno, Victoria Warren-Mears, Tracy A. Battaglia

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Objective: As part of the Patient Navigation Research Program, we examined the effect of patient navigation versus usual care on timely diagnostic follow-up, defined as clinical management for women with cervical abnormalities within accepted time frames. Methods: Participants from four Patient Navigation Research Program centers were divided into low-and high-risk abnormality groups and analyzed separately. Low-risk participants (n = 2088) were those who enrolled with an initial Pap test finding of atypical squamous cells of undetermined significance (ASCUS) with a positive high-risk human papillomavirus (HPV) serotype, atypical glandular cells, or low-grade squamous intraepithelial lesion (LGSIL). High-risk participants were those with an initial finding of high-grade squamous intraepithelial lesion (HGSIL) (n = 229). A dichotomous outcome of timely diagnostic follow-up within 180 days was used for the low-risk abnormality group and timely diagnostic follow-up within 60 days for the high-risk group, consistent with treatment guidelines. A logistic mixed-effects regression model was used to evaluate the intervention effect using a random effect for study arm within an institution. A backward selection process was used for multivariable model building, considering the impact of each predictor on the intervention effect. Results: Low-risk women in the patient navigation arm showed an improvement in the odds of timely diagnostic follow-up across all racial groups, but statistically significant effects were only observed in non-English-speaking Hispanics (OR 5.88, 95% CI 2.81-12.29). No effect was observed among high-risk women. Conclusion: These results suggest that patient navigation can improve timely diagnostic follow-up among women with low-risk cervical abnormalities, particularly in non-English-speaking Hispanic women.

Original languageEnglish (US)
Pages (from-to)15-21
Number of pages7
JournalJournal of Women's Health
Issue number1
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • General Medicine


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