163. Immunologische Folgen des Milzverlustes nach Splenektomie bei traumatischer Milzruptur

H. J. Klotter; H. Schulte-Wissermann; K. Rückert; R. Grüssner

doi:10.1007/BF01274481

163. Immunologische Folgen des Milzverlustes nach Splenektomie bei traumatischer Milzruptur

Translated title of the contribution: Immunologic changes following splenectomy for traumatic splenic rupture

H. J. Klotter, H. Schulte-Wissermann, K. Rückert, R. Grüssner

Research output: Contribution to journal › Article › peer-review

Abstract

After splenectomy for traumatic spleen rupture, 97 patients were followed up 2-18 years later. None had suffered from the OPSI syndrome. In 53% of the splenectomized patients, Howell-Jolly bodies and statistically significant monocytosis were detected. Sintigraphically proven peritoneal splenosis was present in 75% of the patients; however, no specific filtration was demonstrated by dynamic scintigraphy. Of the patients without splenosis who were followed up, 15 had a significant reduction of the killing activity of neutrophile granulocytes, as well as decreased numbers of T-helper cells. The T₄/T₈ ratio was 1:0.

Translated title of the contribution	Immunologic changes following splenectomy for traumatic splenic rupture
Original language	German
Pages (from-to)	730
Number of pages	1
Journal	Langenbecks Archiv für Chirurgie
Volume	369
Issue number	1
DOIs	https://doi.org/10.1007/BF01274481
State	Published - Dec 1986
Externally published	Yes

Keywords

Immunological changes
Traumatic splenic rupture

ASJC Scopus subject areas

Surgery

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AU - Rückert, K.

AU - Grüssner, R.

PY - 1986/12

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N2 - After splenectomy for traumatic spleen rupture, 97 patients were followed up 2-18 years later. None had suffered from the OPSI syndrome. In 53% of the splenectomized patients, Howell-Jolly bodies and statistically significant monocytosis were detected. Sintigraphically proven peritoneal splenosis was present in 75% of the patients; however, no specific filtration was demonstrated by dynamic scintigraphy. Of the patients without splenosis who were followed up, 15 had a significant reduction of the killing activity of neutrophile granulocytes, as well as decreased numbers of T-helper cells. The T4/T8 ratio was 1:0.

AB - After splenectomy for traumatic spleen rupture, 97 patients were followed up 2-18 years later. None had suffered from the OPSI syndrome. In 53% of the splenectomized patients, Howell-Jolly bodies and statistically significant monocytosis were detected. Sintigraphically proven peritoneal splenosis was present in 75% of the patients; however, no specific filtration was demonstrated by dynamic scintigraphy. Of the patients without splenosis who were followed up, 15 had a significant reduction of the killing activity of neutrophile granulocytes, as well as decreased numbers of T-helper cells. The T4/T8 ratio was 1:0.

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163. Immunologische Folgen des Milzverlustes nach Splenektomie bei traumatischer Milzruptur

Abstract

Keywords

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