Immunologic aspects of malignancy. II. Host immunocompetence and relationship to the clinical stage in patients with prostatic cancer

R. J. Ablin, P. D. Guinan, E. R. Rios

Research output: Contribution to journalArticlepeer-review

Abstract

As knowledge of the stage and grade of tumour are essential to the selection of the appropriate therapeutic modality and subsequent management of the patient, the patient's immunological competence is equally significant. In the present communication a broad spectrum of cellular and humorally mediated parameters of immunologic responsiveness reflecting more or less general immunocompetence rather than tumour specific immunity were evaluated in 28 patients with the prostatic cancer. The immunocompetence of these patients was then 'immunostaged' independently without prior knowledge of their clinical stage, and the correlation and significance of these determinations evaluated. In this present preliminary report, a statistically significant correlation (P<0.05) was observed between the patients' 'immunostage' and clinical stage.

Original languageEnglish (US)
Pages (from-to)247-254
Number of pages8
JournalAllergologia et Immunopathologia
Volume4
Issue number4
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine

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