Abstract
An immunochemical analysis of the Ly-8.2 antigen was performed. Reactivity of B10-radiolabeled T and B cell lysates with a C3H anti-AKR serum immunoprecipitates a major 43,000 m.w. protein detectable by one-dimensional gel electrophoresis. This protein can be radioiodinated, however, it does not appear to bind to lentil lectin. Two-dimensional gel electrophoresis and peptide-mapping studies indicate that this protein is structurally very similar to lymphocyte actin. The possible molecular relationship between Ly-8.2, other lymphocyte membrane antigens, and actin is discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 326-333 |
| Number of pages | 8 |
| Journal | Journal of Immunology |
| Volume | 122 |
| Issue number | 1 |
| State | Published - 1979 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology