Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy

Elizabeth Connick; Madeleine A. Kane; Irene E. White; John Ryder; Thomas B. Campbell

doi:10.1086/426078

Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy

Elizabeth Connick
, Madeleine A. Kane
, Irene E. White
, John Ryder
, Thomas B. Campbell

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

Rapidly progressive Kaposi sarcoma (KS) lesions with lymph-adenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4⁺ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4⁺ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.

Original language	English (US)
Pages (from-to)	1852-1855
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	39
Issue number	12
DOIs	https://doi.org/10.1086/426078
State	Published - Dec 15 2004
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1086/426078

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abstract = "Rapidly progressive Kaposi sarcoma (KS) lesions with lymph-adenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4+ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4+ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.",

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AU - Connick, Elizabeth

AU - Kane, Madeleine A.

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AU - Ryder, John

AU - Campbell, Thomas B.

PY - 2004/12/15

Y1 - 2004/12/15

N2 - Rapidly progressive Kaposi sarcoma (KS) lesions with lymph-adenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4+ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4+ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.

AB - Rapidly progressive Kaposi sarcoma (KS) lesions with lymph-adenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4+ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4+ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.

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Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy

Abstract

ASJC Scopus subject areas

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