Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma during potent antiretroviral therapy

Elizabeth Connick, Madeleine A. Kane, Irene E. White, John Ryder, Thomas B. Campbell

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

Rapidly progressive Kaposi sarcoma (KS) lesions with lymph-adenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4+ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4+ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.

Original languageEnglish (US)
Pages (from-to)1852-1855
Number of pages4
JournalClinical Infectious Diseases
Volume39
Issue number12
DOIs
StatePublished - Dec 15 2004
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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