Abstract
We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool-purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1077-1081 |
| Number of pages | 5 |
| Journal | Journal of Experimental Medicine |
| Volume | 145 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 1977 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
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