TY - JOUR
T1 - Immune mechanisms in leukemia
T2 - Role of the ia antigens*
AU - Lukasewycz, Omelan A.
AU - Frelinger, Jeffrey A.
PY - 1977/4/1
Y1 - 1977/4/1
N2 - We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool-purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.
AB - We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool-purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.
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U2 - 10.1084/jem.145.4.1077
DO - 10.1084/jem.145.4.1077
M3 - Article
C2 - 67166
AN - SCOPUS:0017722242
SN - 0022-1007
VL - 145
SP - 1077
EP - 1081
JO - Journal of Experimental Medicine
JF - Journal of Experimental Medicine
IS - 4
ER -