Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis

Russell S. Witte, Michael J Bernas

Research output: Chapter in Book/Report/Conference proceedingChapter


Imaging plays a crucial role in the fundamental understanding of lymphatic system structure and function throughout the body both in health and a wide variety of clinical disorders. It also has application to identify primary and metastatic cancer spread to regional nodes/organs as well as its importance in cancer assessment/treatment planning using the sentinel node protocol. There are multiple different techniques utilizing associated tracers for in vivo dynamic imaging in both humans and experimental models, and the future continues to offer advancements including theranostics. Each technique has strengths and weaknesses for specific applications. Individual techniques (and sometimes in combination) produce images for the diagnosis, treatment monitoring, and even to develop new treatment strategies for cancer and cancer-related sequelae.

Original languageEnglish (US)
Title of host publicationCancer Metastasis Through the Lymphovascular System
PublisherSpringer International Publishing
Number of pages11
ISBN (Electronic)9783030930844
ISBN (Print)9783030930837
StatePublished - Jan 1 2022


  • Cancer metastasis
  • Fluorescent imaging
  • Lymphatic imaging
  • Lymphography
  • Lymphoscintigraphy
  • Magnetic resonance
  • Photoacoustics

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)


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