TY - JOUR
T1 - Imaging of intracranial haemorrhage
AU - Kidwell, Chelsea S.
AU - Wintermark, Max
N1 - Funding Information:
CSK receives funding from the National Institute of Neurological Disorders and Stroke (U54NS057405 and P50 NS44378). MW receives funding from the National Center for Research Resources (KL2 RR024130), GE Healthcare, Philips Medical Systems, and Boston Scientific. MW is a consultant for Paion, Lundbeck, and Concentric. The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Neurological Disorders and Stroke, the National Center for Research Resources, the National Institutes of Health, and the other sponsors.
PY - 2008/3
Y1 - 2008/3
N2 - Intracranial haemorrhage can be a devastating disorder that requires rapid diagnosis and management. Neuroimaging studies are not only required for diagnosis but also provide important insights into the type of haemorrhage, the underlying aetiology, and the accompanying pathophysiology. Historically, CT has been the diagnostic imaging study of choice; however, there is a growing body of data that suggest that MRI is at least as sensitive as CT to detect haemorrhage in the hyperacute setting, and superior to CT in the subacute and chronic settings. Blood has characteristic appearances on both imaging modalities at each stage (acute, subacute, and chronic) and it is important that physicians are familiar with the appearance of various types of intracranial haemorrhage on CT and MRI and their clinical implications. In addition, new imaging applications, such as magnetic resonance spectroscopy and diffusion tensor imaging, are promising research techniques that have the potential to enhance our understanding of the tissue injury and recovery that result from intracranial haemorrhage.
AB - Intracranial haemorrhage can be a devastating disorder that requires rapid diagnosis and management. Neuroimaging studies are not only required for diagnosis but also provide important insights into the type of haemorrhage, the underlying aetiology, and the accompanying pathophysiology. Historically, CT has been the diagnostic imaging study of choice; however, there is a growing body of data that suggest that MRI is at least as sensitive as CT to detect haemorrhage in the hyperacute setting, and superior to CT in the subacute and chronic settings. Blood has characteristic appearances on both imaging modalities at each stage (acute, subacute, and chronic) and it is important that physicians are familiar with the appearance of various types of intracranial haemorrhage on CT and MRI and their clinical implications. In addition, new imaging applications, such as magnetic resonance spectroscopy and diffusion tensor imaging, are promising research techniques that have the potential to enhance our understanding of the tissue injury and recovery that result from intracranial haemorrhage.
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U2 - 10.1016/S1474-4422(08)70041-3
DO - 10.1016/S1474-4422(08)70041-3
M3 - Review article
C2 - 18275927
AN - SCOPUS:38949157989
SN - 1474-4422
VL - 7
SP - 256
EP - 267
JO - The Lancet Neurology
JF - The Lancet Neurology
IS - 3
ER -