Image reconstruction of optical tomographic data from a highly scattering medium

J. Lee, D. W. Wilson, H. H. Barrett, A. F. Gmitro

Research output: Contribution to journalConference articlepeer-review


Recently new technologies for detecting biomolecules have been developed and are opening a new era of medical imaging. Chemiluminescence and fluorescence are emerging as promising tools for these tasks. These molecules emit optical photons that can be observed outside the body. Unfortunately, they are heavily scattered and absorbed in biological tissue. This is an obstacle for determining a way of mapping an original source distribution. In order to overcome this obstacle, we suggest a new concept, Optical Emission Computed Tomography(OpECT) and test its feasibility with computer simulation.

Original languageEnglish (US)
Pages (from-to)792-799
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2001
EventMedical Imaging 2001: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2001Feb 20 2001


  • Chemiluminescene
  • Fluorescence
  • ML-EM algorithm
  • Monte-Carlo Simulation
  • OpECT
  • Scattering Medium

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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