Idiotypic inheritance: Allelic relationships between immunoglobulin genes

A. L.M. Bothwell

doi:10.1016/S0769-2625(84)80011-2

Idiotypic inheritance: Allelic relationships between immunoglobulin genes

Research output: Contribution to journal › Article › peer-review

Abstract

An analysis of genes related to the expressed V_H region of anti-NP antibodies in C57BL/6 mice showed that 24 distinct genes could be grouped into 3 subfamilies. Some of these genes showed striking homology with a family found in BALB/c mice. The extension of diversity through gene conversion seems to be very important in the V_H family.

Original language	English (US)
Pages (from-to)	51-55
Number of pages	5
Journal	Annales de l'Institut Pasteur - Immunology
Volume	135
Issue number	1
DOIs	https://doi.org/10.1016/S0769-2625(84)80011-2
State	Published - 1984
Externally published	Yes

Keywords

Allelism
Allélisme
Conversion génique
Gene conversion
Gènes V anti-NP
Idiotypie
Idiotypy
Immunogenesis
Immunogenèse
Immunoglobulin
Immunoglobuline
NP V genes

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/S0769-2625(84)80011-2

Cite this

@article{70dc877283ec466293ecb6a2deae82d2,

title = "Idiotypic inheritance: Allelic relationships between immunoglobulin genes",

abstract = "An analysis of genes related to the expressed VH region of anti-NP antibodies in C57BL/6 mice showed that 24 distinct genes could be grouped into 3 subfamilies. Some of these genes showed striking homology with a family found in BALB/c mice. The extension of diversity through gene conversion seems to be very important in the VH family.",

keywords = "Allelism, All{\'e}lisme, Conversion g{\'e}nique, Gene conversion, G{\`e}nes V anti-NP, Idiotypie, Idiotypy, Immunogenesis, Immunogen{\`e}se, Immunoglobulin, Immunoglobuline, NP V genes",

author = "Bothwell, {A. L.M.}",

year = "1984",

doi = "10.1016/S0769-2625(84)80011-2",

language = "English (US)",

volume = "135",

pages = "51--55",

journal = "Annales de l'Institut Pasteur - Immunology",

issn = "0769-2625",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - Idiotypic inheritance

T2 - Allelic relationships between immunoglobulin genes

AU - Bothwell, A. L.M.

PY - 1984

Y1 - 1984

N2 - An analysis of genes related to the expressed VH region of anti-NP antibodies in C57BL/6 mice showed that 24 distinct genes could be grouped into 3 subfamilies. Some of these genes showed striking homology with a family found in BALB/c mice. The extension of diversity through gene conversion seems to be very important in the VH family.

AB - An analysis of genes related to the expressed VH region of anti-NP antibodies in C57BL/6 mice showed that 24 distinct genes could be grouped into 3 subfamilies. Some of these genes showed striking homology with a family found in BALB/c mice. The extension of diversity through gene conversion seems to be very important in the VH family.

KW - Allelism

KW - Allélisme

KW - Conversion génique

KW - Gene conversion

KW - Gènes V anti-NP

KW - Idiotypie

KW - Idiotypy

KW - Immunogenesis

KW - Immunogenèse

KW - Immunoglobulin

KW - Immunoglobuline

KW - NP V genes

UR - http://www.scopus.com/inward/record.url?scp=0021341173&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021341173&partnerID=8YFLogxK

U2 - 10.1016/S0769-2625(84)80011-2

DO - 10.1016/S0769-2625(84)80011-2

M3 - Article

C2 - 6712162

AN - SCOPUS:0021341173

SN - 0769-2625

VL - 135

SP - 51

EP - 55

JO - Annales de l'Institut Pasteur - Immunology

JF - Annales de l'Institut Pasteur - Immunology

IS - 1

ER -

Idiotypic inheritance: Allelic relationships between immunoglobulin genes

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this