Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

Henk J. Swarts; Frank J.M. Verhagen; Jim A. Field; Joannes B.P.A. Wijnberg

doi:10.1021/np980164h

Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

Henk J. Swarts, Frank J.M. Verhagen, Jim A. Field, Joannes B.P.A. Wijnberg

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1- (3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (2) and 1-(3'-chloro-4'- methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp, BOS55 was also a new finding.

Original language	English (US)
Pages (from-to)	1110-1114
Number of pages	5
Journal	Journal Of Natural Products
Volume	61
Issue number	9
DOIs	https://doi.org/10.1021/np980164h
State	Published - Sep 1998
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species",

abstract = "Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1- (3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (2) and 1-(3'-chloro-4'- methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp, BOS55 was also a new finding.",

author = "Swarts, {Henk J.} and Verhagen, {Frank J.M.} and Field, {Jim A.} and Wijnberg, {Joannes B.P.A.}",

year = "1998",

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T1 - Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

AU - Swarts, Henk J.

AU - Verhagen, Frank J.M.

AU - Field, Jim A.

AU - Wijnberg, Joannes B.P.A.

PY - 1998/9

Y1 - 1998/9

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AB - Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1- (3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (2) and 1-(3'-chloro-4'- methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp, BOS55 was also a new finding.

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Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

Abstract

ASJC Scopus subject areas

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