Ia antigens on non-lymphoid tissues their origins and functions

Douglas F. Nixon; Jenny Pan Yun Ting; Jeffrey A. Frelinger

doi:10.1016/0167-5699(82)90019-6

Ia antigens on non-lymphoid tissues their origins and functions

Douglas F. Nixon, Jenny Pan Yun Ting, Jeffrey A. Frelinger

Immunobiology

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Abstract

Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B cells, subsets of T helper and T suppressor cells and accessory, antigen-presenting cells are Ia-positive (Ia+) while T killer cells and natural killer cells are not. This article discusses the nature and function of Ia+ cells found in non-lymphoid tissues, some of which are immunologically involved while others are not obviously so.

Original language	English (US)
Pages (from-to)	339-342
Number of pages	4
Journal	Immunology Today
Volume	3
Issue number	12
DOIs	https://doi.org/10.1016/0167-5699(82)90019-6
State	Published - Dec 1982

ASJC Scopus subject areas

Immunology

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10.1016/0167-5699(82)90019-6

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@article{548d539216794f8ab82a20187a22da58,

title = "Ia antigens on non-lymphoid tissues their origins and functions",

abstract = "Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B cells, subsets of T helper and T suppressor cells and accessory, antigen-presenting cells are Ia-positive (Ia+) while T killer cells and natural killer cells are not. This article discusses the nature and function of Ia+ cells found in non-lymphoid tissues, some of which are immunologically involved while others are not obviously so.",

author = "Nixon, {Douglas F.} and Ting, {Jenny Pan Yun} and Frelinger, {Jeffrey A.}",

note = "Funding Information: Work described from our laboratory was supported by grants from the National Institutes of Health (CA 22662) and the Kroc and Wright Foundations. D.F.N. is supported by the Wright Foundation, J.P.Y.T. is an American Cancer Society postdoctoral fellow and J.A.F. is the recipient of an American Cancer Society Faculty Research Award.",

year = "1982",

month = dec,

doi = "10.1016/0167-5699(82)90019-6",

language = "English (US)",

volume = "3",

pages = "339--342",

journal = "Immunology Today",

issn = "0167-5699",

publisher = "Elsevier Limited",

number = "12",

}

TY - JOUR

T1 - Ia antigens on non-lymphoid tissues their origins and functions

AU - Nixon, Douglas F.

AU - Ting, Jenny Pan Yun

AU - Frelinger, Jeffrey A.

N1 - Funding Information: Work described from our laboratory was supported by grants from the National Institutes of Health (CA 22662) and the Kroc and Wright Foundations. D.F.N. is supported by the Wright Foundation, J.P.Y.T. is an American Cancer Society postdoctoral fellow and J.A.F. is the recipient of an American Cancer Society Faculty Research Award.

PY - 1982/12

Y1 - 1982/12

N2 - Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B cells, subsets of T helper and T suppressor cells and accessory, antigen-presenting cells are Ia-positive (Ia+) while T killer cells and natural killer cells are not. This article discusses the nature and function of Ia+ cells found in non-lymphoid tissues, some of which are immunologically involved while others are not obviously so.

AB - Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B cells, subsets of T helper and T suppressor cells and accessory, antigen-presenting cells are Ia-positive (Ia+) while T killer cells and natural killer cells are not. This article discusses the nature and function of Ia+ cells found in non-lymphoid tissues, some of which are immunologically involved while others are not obviously so.

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DO - 10.1016/0167-5699(82)90019-6

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AN - SCOPUS:2442499823

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SP - 339

EP - 342

JO - Immunology Today

JF - Immunology Today

IS - 12

ER -

Ia antigens on non-lymphoid tissues their origins and functions

Abstract

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