Hypersensitivity pneumonitis from Pezizia domiciliana: A case of El Nino lung

Robert S. Wright, Zeb Dyer, Myron I. Liebhaber, Donna L. Kell, Philip Harber

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


A previously healthy woman developed severe dyspnea and was found to have restrictive lung disease and evidence of alveolitis. Open lung biopsy revealed extrinsic allergic alveolitis (hypersensitivity pneumonitis). The etiology was not initially apparent, but a home inspection showed an unusual mushroom growing in the patient's basement. Air sampling and serum precipitins against the fungal antigens confirmed that Pezizia domiciliana was the cause of the patient's hypersensitivity pneumonitis. This is the first described case of hypersensitivity pneumonitis cause by P. domiciliana. We speculate that unprecedented rainfall and flooding of the patient's basement as a result of El Nino rains produced ideal factors for the growth of this fungus.

Original languageEnglish (US)
Pages (from-to)1758-1761
Number of pages4
JournalAmerican journal of respiratory and critical care medicine
Issue number5 I
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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