Hydrolysis of phosphonoformate esters: Product distribution and reactivity patterns

E. S. Krol, Jean M. Davis, Gregory R.J. Thatcher

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Phosphonoformate triesters are hydrolysed to mixtures of hydrogen phosphonate and phosphonoformate esters and free acids; the rates and product distribution are dependent on pH and ester leaving group abilities.

Original languageEnglish (US)
Pages (from-to)118-119
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number2
DOIs
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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