@inproceedings{b9535d11d78249b6aca6dadb11131c4c,
title = "HuMiX: A microfluidics-based in vitro co-culture device for investigating host-microbe molecular interactions",
abstract = "Lack of in vitro co-culture devices hinder investigations aiming to uncover the role of human-associated microbial community imbalances in causation of numerous medical conditions. We describe the development and validation of a microfluidics-based co-culture device (HuMiX) allowing co-cultivation of human and microbial cells. The modular device architecture provides access to individual co-cultured contingents following targeted perturbations which facilitate high resolution systemic investigations into the hypothesized role of the complex host-microbial molecular interactions in the pathogenesis of idiopathic medical conditions.",
keywords = "Co-culture, Gut on chip, Host-Microbe interaction, Microbiome, Organs on chip",
author = "Pranjul Shah and Joelle Fritz and Matt Estes and Frederic Zenhausern and Paul Wilmes",
note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",
year = "2014",
language = "English (US)",
series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
publisher = "Chemical and Biological Microsystems Society",
pages = "300--302",
booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
}