HLA in Egyptian children with biliary atresia

Hassan H. A-Kader; Moustafa El-Ayyouti; Samia Hawas; Ahmed Abdalla; Yousif Al-Tonbary; Mohammed Bassiouny; Anna Boneberg; Shadia El-Sallab

doi:10.1067/mpd.2002.127506

HLA in Egyptian children with biliary atresia

Hassan H. A-Kader, Moustafa El-Ayyouti, Samia Hawas, Ahmed Abdalla, Yousif Al-Tonbary, Mohammed Bassiouny, Anna Boneberg, Shadia El-Sallab

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

Original language	English (US)
Pages (from-to)	432-434
Number of pages	3
Journal	Journal of Pediatrics
Volume	141
Issue number	3
DOIs	https://doi.org/10.1067/mpd.2002.127506
State	Published - Sep 2002
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1067/mpd.2002.127506

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title = "HLA in Egyptian children with biliary atresia",

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T1 - HLA in Egyptian children with biliary atresia

AU - A-Kader, Hassan H.

AU - El-Ayyouti, Moustafa

AU - Hawas, Samia

AU - Abdalla, Ahmed

AU - Al-Tonbary, Yousif

AU - Bassiouny, Mohammed

AU - Boneberg, Anna

AU - El-Sallab, Shadia

PY - 2002/9

Y1 - 2002/9

N2 - We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

AB - We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

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JF - Journal of Pediatrics

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ER -

HLA in Egyptian children with biliary atresia

Abstract

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